EPA-Registered Biodecontamination for Emerging Viral Threats: Ebola, Hantavirus, COVID-19, H5N1, & More

CUROXIDE™ (EPA Reg. No. 93324-1) is listed on EPA's List Q: Disinfectants for Emerging Viral Pathogens, qualified across all three viral tiers—including Tier 1, the hardest-to-kill non-enveloped viruses. EPA List Q is the federal benchmark for emerging viral pathogen readiness. CURIS is one of a select number of biodecontamination systems to meet this standard. 

Biodecontamination in the Age of COVID-19, Ebola, Mpox, Hantavirus, and Bird Flu (H5N1)

Addressing complex pathogens, from the variants of COVID-19 to the challenges of Ebola, Hantavirus, Mpox (Monkeypox),  and Bird Flu (H5N1) requires an informed and adaptable approach. CURIS's systems are designed based on empirical evidence, ensuring that they remain effective against the present and emerging threats.

 

The Latest Emerging Viral Threats

Recent concerns over a number of viruses, such as Bird Flu (H5N1) among others, have prompted organizations and facilities to ramp up their emergency preparedness by seeking hydrogen peroxide decontamination solutions for emerging viral threats.  

CURoxide™ (EPA Reg. No. 93324-1), the hydrogen peroxide solution used by the CURIS System, is listed on EPA’s List Q: Disinfectants for Emerging Viral Pathogens (EVPs)—qualified across all three viral tiers (enveloped, large non-enveloped, and small non-enveloped). Under EPA’s Emerging Viral Pathogen policy, this means CURoxide™ is expected to be effective against emerging viruses such as Ebola, Hantavirus, Mpox, and SARS-CoV-2 (COVID-19) when used according to the directions for use against C. difficile.

Additionally, CURIS System has demonstrated a 10-log reduction of viruses including Adenovirus on both porous and nonporous materials (White Paper: Confirmation of Virological Suitability — HC.N95DeconPS). 

CURoxide™ is also registered with Health Canada as a disinfectant (DIN 02524988).


HVAC and HEPA Decontamination

In a world where clean air is paramount, CURIS takes a giant leap forward. Our groundbreaking system moves beyond the confines of traditional filtration, not just trapping but actively neutralizing harmful pathogens within HVAC & HEPA filters. This approach assures that the air circulating in our environments isn’t just clean, but pure and safe.

  • CURIS proudly achieves a 99.9999% kill rate of bacterial spores, ensuring harmful agents are neutralized before air recirculation.
  • CURoxide™ is included on EPA List: N for use against SARS-CoV-2, the virus that causes COVID-19, supporting facility readiness through evolving variants.

Room and Space Biodecontamination

Environments, irrespective of size or function, are susceptible to harmful pathogens. CURIS has pioneered a method using hydrogen peroxide fogging that ensures every nook and cranny of a room is disinfected. This comprehensive approach eclipses traditional disinfection methods, ensuring all spaces—be it a classroom, office, or living area—are genuinely free from contagion.

  • Ebola virus is a hemorrhagic fever and enveloped virus—the easiest viral class to inactivate. Under EPA’s Emerging Viral Pathogen policy, CURoxide™ (qualified across all three viral tiers via its C. difficile claim) is expected to be effective against Ebola virus when used according to the directions for use against C. difficile.
  • When Ebola re-emerged in 2019, CURIS demonstrated effectiveness against this high-consequence pathogen. As hemorrhagic fever viruses remain a persistent global biosafety concern, CURIS systems are designed and validated to support facility readiness for current and future high-risk viral threats. 
  • As we face the threats of today and tomorrow, CURIS adapts and responds. Mpox (Monkeypox) is an enveloped virus. Under EPA’s Emerging Viral Pathogen policy, CURoxide™ is expected to be effective against Mpox when used according to its C. difficile directions for use.

Targeted Surface Disinfection

Every surface tells a story—a story of countless interactions, touchpoints, and potential disease transmission. CURIS rewrites this narrative. Through targeted disinfection, we ensure that frequently touched surfaces, from door knobs to countertops, aren't just cleaned but are truly disinfected, breaking the chain of potential infection.

  • Pathogens like norovirus are notorious for their persistence, with the ability to linger and infect for extended periods. CURIS is equipped to combat these resilient threats, providing peace of mind with every spray.
  • In an ever-evolving microbial world, CURIS remains ahead of the curve, tailoring its approach to counter both established threats and emerging ones that loom on the horizon.

CURIS Applications


Room & RABS Decontamination

CURIS 3

Engineered for comprehensive room and enclosure decontamination, the CURIS 3 system is designed to enhance your facility’s safety and compliance standards, helping you maintain sterility assurance across a wide range of applications.

 

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BSC & Filter Housing Decontamination

TRINITY

TRINITY provides a modular solution for BSC and filter housing decontamination, supporting product and personnel protection while helping maintain aseptic conditions wherever critical work is performed.

 

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Integrated Isolator Decontamination

7000ei

The 7000ei system is designed for the unique challenges of closed systems, such as isolators, delivering reliable decontamination while preserving the integrity of sealed, sterile environments essential for quality and safety.

 

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Passthrough, Chamber, & Enclosures

CURIS Custom Facility Integration

Custom Facility Integration can safeguard a single enclosure, a suite of rooms, or your entire facility, providing tailored integration of decontamination technology to support consistent, repeatable contamination control in your space and for your transfer environment (MAL).

 

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Decontamination & Validation

CURIS Services

CURIS Services help strengthen your facility’s safety and compliance programs, offering biodecontamination services along with Installation, Operational, and Performance Qualification (IQ/OQ/PQ) and preventive maintenance, so your team can stay focused on core operations.

 

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Data Compliance

CSDM

Streamline your decontamination workflows with CSDM, a cloud-based data and compliance platform that manages automated jobs, data logging, report generation, and more to support seamless, traceable, and auditable practices across diverse regulated environments.

 

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Why Choose CURIS?


advanced contamination control solutions

CURIS Technology for Emerging Viral Threats

CURIS leads the field in advanced contamination control solutions. Our patented HHP™ (Hybrid Hydrogen Peroxide), Rapid Vapor™, and Pulse™ technologies deliver unsurpassed biodecontamination for a wide range of sectors. Whether it's life sciences, healthcare, or the public sector, our solutions offer unparalleled protection.
Experience the CURIS difference
validation for regulatory compliance Annex 1

CURIS Validation

CURIS sets the bar high with EPA, FDA, and Annex I regulatory compliance. Our safer*, validatable, repeatable ≥6 log* efficacy is uniquely tailored to your specific needs. Choose CURIS, not only for superior solutions but also as a dependable partner committed to safety and quality assurance.
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